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INRAE 24, chemin de Borde Rouge –Auzeville – CS52627 31326 Castanet Tolosan cedex - France

Edito

Welcome to our Inrae network

This site aims to create links between researchers working within INRAE and their collaborators on the theme of extracellular vesicles, in order to generate technical and scientific collaborations, and to promote the emergence of networks to respond to calls of offer.

Welcome to the INRAE extracellular vesicle research network

Following an initial meeting held on September 29th, 2023 at INRAE Institute in Paris, which brought together over 40 researchers from all departments, we have decided to create this website. Its purpose is to create links between researchers working at INRAE and their collaborators on the topic of extracellular vesicles (EVs), to encourage technical and scientific collaboration, and to promote the emergence of networks to respond to calls.

Extracellular vesicles (EVs) are nanovesicles surrounded by a lipid bilayer released by cells into the extracellular environment, playing a crucial role in intercellular communication and implicated in various biological processes. At INRAE, research on extracellular vesicles focuses primarily on their role and application in the fields of agriculture, food and the environment. Here are just a few of our specific areas of research

-Biotechnology and Animal Health:

*Study of EVs as vectors to improve the health and productivity of farm animals.

*Research into the use of EVs to diagnose and treat animal diseases, exploring their potential as biomarkers and therapeutic agents.

-Crop Improvement and Stress Resistance:

*Investigating the role of EVs in defense mechanisms against pathogens, environmental stresses, development, etc.

*Use of EVs to modulate plant responses to infections and stress conditions, aiming to improve crop resilience and productivity.

-Microbiology and Host-Microbe Interactions:

*Analysis of EVs produced by microorganisms (bacteria, fungi, etc.) and their impact on plants and animals.

*Studies of the interactions between EVs from microorganisms and the immune systems of plants and animals, aiming to understand and exploit these interactions for applications in human nutrition and animal health.

-Food Innovation:

*Research into the use of EVs in food processing, for example to improve nutrient stability and bioavailability.

*Exploring EVs as tools for developing functional foods with human health benefits.

*Understanding the role of EVs in the development of metabolic diseases.

-Environment and Ecology:

*Research into the impact of EVs on interactions between organisms, contributing to a better understanding of ecosystem dynamics.

*Research into the link between EVs and pollutants (response of organisms to pollutants, pollutant transport betwen cells, etc.).

INRAE conducts this research in collaboration with academic, industrial and international partners, integrating multidisciplinary approaches ranging from molecular and cellular biology to ecology and biotechnology.

This site is intended to evolve according to your wishes and needs. Please do not hesitate to contact us if you feel that information is missing, or to send us your latest published work.

Sophie Rome, Laurent Galio